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Efficacy of infliximab biosimilars in patients with Crohn's disease 2 The prespecified margin of non-inferiority was 15%. In patients with Crohn's disease, the non-inferiority margin was 15·3%, which was above the pre-specified non-inferiority margin. However, the adjusted difference in efficacy reported, for which the statistical methods are not presented in the Article, ...
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Endocannabinoid-specific impairment in synaptic plasticity in striatum of Huntington's disease ... Abstract. Huntington's disease (HD) is an inherited neurodegenerative disease affecting predominantly striatum and cortex that results in motor and cognitive disorders. Prior to a motor phenotype, animal models of HD show aberrant cortical-striatal glutamate signaling. Here, we tested synaptic plasticity ...
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